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Care During Chemotherapy and Beyond

Acronym: Hyper-CVAD

Most often associated with treatment of Acute Lymphocytic Leukemia (ALL)

(Cytoxan®, Neosar®)

Cancers treated with cyclophosphamide include: Hodgkin’s and non-Hodgkin's lymphoma, Burkitt’s lymphoma, chronic lymphocytic leukemia (CLL), chronic myelocytic leukemia (CML), acute myelocytic leukemia (AML), acute lymphocytic leukemia (ALL), t-cell lymphoma (mycosis fungoides), multiple myeloma, neuroblastoma, retinoblastoma, rhabdomyosarcoma, Ewing's sarcoma; breast, testicular, endometrial, ovarian, and lung cancers, and in conditioning regimens for bone marrow transplantation.

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(Adriamycin ®, Rubex)

Cancers treated with Doxorubicin include: bladder, breast, head and neck, leukemia (some types), liver, lung, lymphomas, mesothelioma, multiple myeloma, neuroblastoma, ovary, pancreas, prostate, sarcomas, stomach, testis (germ cell), thyroid, uterus.

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(Oncovin ®, Vincasar Pfs, Vincristine Sulfate, LCR, VCR)

Cancers treated with Vincristine include: acute leukemia, Hodgkin's and non- Hodgkin's lymphoma, neuroblastoma, rhabdomyosarcoma, Ewing's sarcoma, Wilms' tumor, multiple myeloma, chronic leukemias, thyroid cancer, brain tumors.

It is also used to treat some blood disorders.

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(Decadron, Dexasone, Diodex, Hexadrol, Maxidex, dexamethasone sodium phosphate, dexamethasone acetate)

As an anti-inflammatory medication. Dexamethasone relieves inflammation in various parts of the body. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain, and to treat eye inflammation.

To treat or prevent allergic reactions.

As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions.

As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma.

To treat nausea and vomiting associated with some chemotherapy drugs.

Used to stimulate appetite in cancer patients with severe appetite problems.

Also used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).

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(Mesnex)

Prevention of ifosfamide-induced hemorrhagic cystitis (syndrome of bleeding and irritation of the bladder).

Prevention of high-dose cyclophosphamide-induced hemorrhagic cystitis.

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(Rheumatrex®, TrexallTM, Amethopterin, Methotrexate Sodium, MTX)

Used in the treatment of breast, head and neck, lung, stomach, and esophagus cancers. Acute lymphoblastic leukemia (ALL), sarcomas, non-Hodgkin's lymphoma (NHL), gestational trophoblastic cancer, and mycosis fungoides (cutaneous T-cell lymphoma).

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(Calcium Leucovorin, Citrovorum Factor, Folinic Acid)

In combination with fluoruracil to treat cancers such as; colon and rectal, head and neck, esophageal, and other cancers of the gastrointestinal tract.

As an antidote to effects of certain chemotherapy drugs such as methotrexate.

Treatment of megaloblastic anemia when folic acid deficiency is present.

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(Cytosar-U, Ara-C, Arabinosylcytosine)

Cytarabine is used to treat different forms of leukemia, including acute and chronic myelogenous (AML and CML) and acute lymphocytic leukemia (ALL). It is also used to treat lymphoma, meningeal leukemia and lymphoma (cancers found in the lining of the brain and spinal cord)

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