Acronym: MFL

(Rheumatrex®, TrexallTM, Amethopterin, Methotrexate Sodium, MTX)

Used in the treatment of breast, head and neck, lung, stomach, and esophagus cancers. Acute lymphoblastic leukemia (ALL), sarcomas, non-Hodgkin's lymphoma (NHL), gestational trophoblastic cancer, and mycosis fungoides (cutaneous T-cell lymphoma).

(Fluorouracil, Adrucil®)

Colon and rectal cancer, Breast cancer, Gastrointestinal cancers including: anal, esphageal, pancreas and gastric (stomach). Head and neck cancer, Hepatoma (liver cancer). Ovarian cancer. Topical use (cream or solution) in basal cell cancer of the skin and actinic keratoses.

(Calcium Leucovorin, Citrovorum Factor, Folinic Acid)

In combination with fluoruracil to treat cancers such as; colon and rectal, head and neck, esophageal, and other cancers of the gastrointestinal tract.

As an antidote to effects of certain chemotherapy drugs such as methotrexate.

Treatment of megaloblastic anemia when folic acid deficiency is present.