Acronym: MINE

(Mesnex)

Prevention of ifosfamide-induced hemorrhagic cystitis (syndrome of bleeding and irritation of the bladder).

Prevention of high-dose cyclophosphamide-induced hemorrhagic cystitis.

(Ifex®)

Ifosfamide is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as an "alkylating agent."

Ifosfamide is give through an infusion into a vein (intravenous, IV).

The amount of ifosfamide that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

(Novantrone, DHAD)

Mitoxantrone is used for advanced prostate cancer not responding to hormone treatment - used in combination with steroids. Acute myelogenous leukemia (AML), Breast cancer and Non-Hodgkin's lymphoma

(Toposar®, VePesid®, Etopophos®, VP-16, Etoposide phosphate)

Testicular, bladder, prostate, lung, stomach, and uterine, cancers. Hodgkin's and non-Hodgkin's lymphoma, mycosis fungoides, Kaposi's sarcoma, Wilm's tumor, rhabdomyosarcoma, Ewing's sarcoma, neuroblastoma, brain tumors.

It also may be given as high-dose therapy in bone marrow transplant setting.