Care During Chemotherapy and Beyond
Generic Name: Epoetin Alfa
PROCRIT is a colony stimulating factor. It is a medication for the treatment
of anemia. (For more detail, see "How PROCRIT Works" section below).
What PROCRIT Is Used For:
- PROCRIT is a supportive care medication. It does not treat cancer.
- It is used to treat anemia caused by chemotherapy cancer treatment.
- PROCRIT is not indicated for patients with myeloid cancers (cancers that originate
in the bone marrow such as acute myelogenous leukemia).
- PROCRIT is not appropriate for the treatment of anemia from other causes such as
iron or folate deficiency or gastrointestinal bleeding. PROCRIT is not a substitute
for blood transfusion.
How PROCRIT Is Given:
- PROCRIT is given by subcutaneous (layer of tissue between the skin and the
muscle) injection into the arm, abdomen or thigh.
- The amount of PROCRIT you receive depends on many factors, including your weight,
your general health, any other health problems you may have, and how your body responds
to it. Your doctor will determine your exact dose and schedule.
Important things to remember about the side effects of PROCRIT:
- Side effects are usually consistent with those typically seen with cancer and chemotherapy.
- Side effects may be reversible and may subside after treatment is complete
The following side effects are common for patients taking PROCRIT:
When to contact your doctor or health care provider:
Contact your health care provider immediately, day or night, if you should experience
any of the following symptoms:
- Tremors or seizures
- Difficulty breathing
- Chest pain
- Sudden severe headache
The following symptoms require medical attention, but are not an emergency.
Contact your health care provider within 24 hours of noticing any of the following:
- Nausea (interferes with ability to eat and urelieved with prescribed medication)
- Vomiting (vomiting more than 4-5 times in a 24-hour period)
- Diarrhea (4-6 episodes in a 24-hour period)
- Swelling of the face, feet, hands, arms or legs
- Swelling, redness and pain in one leg or arm and not the other
Always inform your health care provider if you experience any unusual symptoms.
- Before starting PROCRIT treatment, make sure you tell your doctor about any other
medications you are taking (including over-the-counter drugs, vitamins, or herbal
- PROCRIT should be used with caution in people with high blood pressure or heart
- Inform your health care provider if you are pregnant or may be pregnant prior to
starting this treatment. Pregnancy category C (use in pregnancy only when
benefit to the mother outweighs risk to the fetus).
- Discuss with your doctor when you may safely become pregnant or conceive a child
- It is not known whether PROCRIT is excreted in human milk. Because many drugs
are excreted in human milk, caution should be exercised when PROCRIT is given to
- Consult with your doctor regarding iron supplements while taking PROCRIT.
- If you experience some nausea and vomiting while receiving PROCRIT, but small frequent
meals, chewing gum, lozenges, and good mouth care may help.
- In general, drinking alcoholic beverages should be kept to a minimum or avoided
completely. You should discuss this with your doctor.
- Get plenty of rest.
- Maintain good nutrition.
- If you experience symptoms or side effects, be sure to discuss them with your health
care team. They can prescribe medications and/or offer other suggestions that
are effective in managing such problems.
Monitoring and Testing:
You will be monitored regularly by your doctor while you are taking PROCRIT.
Tests will include blood tests (specifically hemoglobin and hematocrit) and blood
How PROCRIT Works:
In the body's bone marrow (the soft, sponge-like material found inside bones) blood
cells are produced. There are three major types of blood cells; white blood
cells, which fight infection; red blood cells, which carry oxygen to and remove
waste products from organs and tissues; and platelets, which enable the blood to
clot. Cancer treatments such as chemotherapy and radiation therapy can effect
these cells which put a person at risk for developing infections, anemia and bleeding
problems. Colony-stimulating factors are substances that stimulate the production
of blood cells and promote their ability to function. They do not directly
affect tumors but through their role in stimulating blood cells they can be helpful
as support of the person's immune system during cancer treatment.
PROCRIT is identical to a substance your body produces naturally called erythropoietin
(e-rith-ro-poy-e-tin), a protein normally produced by the kidneys which helps
make red blood cells. PROCRIT acts like this natural substance to stimulate
red blood cell production. During chemotherapy, patients may not be able to
produce enough red blood cells, a condition known as anemia. PROCRIT can treat
anemia by increasing the number of red blood cells in the body.
Hemoglobin is the iron-containing substance in red blood cells that delivers oxygen
throughout the body. The normal hemoglobin range is approximately 12 to 18 g/dL,
and varies according to age and gender. Doctors may prescribe PROCRIT to chemotherapy
patients whose hemoglobin levels have fallen below normal levels.
Note: We strongly encourage you to talk with your health care professional about
your specific medical condition and treatments. The information contained in this
website is meant to be helpful and educational, but is not a substitute for medical
Chemocare.com is designed to provide the latest information about chemotherapy to patients and their families, caregivers and friends. For information about the 4th Angel Mentoring Program visit www.4thangel.org