Care During Chemotherapy and Beyond
Trade Name: Arimidex®
Arimidex® is the trade name for the generic drug anastrozole. In some cases, health care professionals may use the trade name Arimidex® when referring to the generic drug name anastrozole.
Anastrozole is a hormone therapy. Anastrozole fights cancer as an "aromatase
inhibitor." (For more detail see "How Anastroloze Works" below).
What Anastrozole Is Used For:
Anastrozole is used to treat breast cancer in postmenopausal women.
Note: If a drug has been approved for one use, physicians sometimes elect to use
this same drug for other problems if they believe it might be helpful.
How Anastrozole Is Given:
- Anastrozole is a pill, taken by mouth.
- You should take anastrozole at about the same time each day. You may take
anastrozole with or without food. If you miss a dose, do not take a
double dose the next day.
- You should not stop taking anastrozole without discussing with your physician.
- The amount of anastrozole that you will receive depends on many factors, including
your general health or other health problems, and the type of cancer or condition
being treated. Your doctor will determine your dose and how long you will
be taking anastrozole.
Side Effects Of Anastrozole:
Important things to remember about the side effects of Anastrozole:
- Most people do not experience all of the side effects listed.
- Side effects are often predictable in terms of their onset and duration.
- Side effects are almost always reversible and will go away after treatment is complete.
- There are many options to help minimize or prevent side effects.
- There is no relationship between the presence or severity of side effects and the
effectiveness of the medication.
The following side effects are common (occurring in greater than 30%) for patients
The following side effects are less common (occurring in 10-29%) for patients taking
Not all side effects are listed above, some that are rare (occurring in less than
10% of patients) are not listed here. However, you should always inform your
health care provider if you experience any unusual symptoms.
When To Contact Your Doctor or Health Care Professional:
The following symptoms require medical attention, but are not emergency situations.
Contact your health care provider within 24 hours of noticing any of the
- Vaginal bleeding (similar to a period)
Always inform your health care provider if you experience any unusual symptoms.
- Before starting Anastrozole treatment, make sure you tell your doctor about any
other medications you are taking (including over-the-counter drugs, vitamins, or
- Inform your health care professional if you are pregnant or may be pregnant prior
to starting this treatment. Pregnancy category D (Anastrozole may be hazardous
to the fetus. Women who are pregnant or become pregnant must be advised of
the potential hazard to the fetus).
- For both men and women: Do not conceive a child (get pregnant) while taking Anastrozole.
Barrier methods of contraception, such as condoms, are recommended. Discuss with
your doctor when you may safely become pregnant or conceive a child after therapy.
- Do not breast feed while taking Anastrozole.
Anastrozole Self Care Tips:
- If you are experiencing hot flashes, wearing light clothing, staying in a cool environment,
and putting cool cloths on your head may reduce symptoms. Consult you health care
provider if these worsen, or become intolerable.
- Acetaminophen or ibuprophen may help relieve discomfort from generalized aches
and pains. However, be sure to talk with your doctor before taking it.
- Anastrozole causes little nausea. However, to reduce nausea, take anti-nausea
medications as prescribed by your doctor, and eat small, frequent meals.
- Get plenty of rest
- Maintain good nutrition
- If you experience symptoms or side effects, be sure to discuss them with your health
care team. They can prescribe medications and/or offer other suggestions that
are effective in managing such problems.
Monitoring and Testing While Taking Anastrozole:
You will be monitored regularly by your doctor while you are taking anastrozole,
but no special tests or blood work are required.
How Anastrozole Works:
Hormones are chemical substances that are produced by glands in the body, which
enter the bloodstream and cause effects in other tissues. For example, the
hormone testosterone made in the testicles and is responsible for male characteristics
such as deepening voice and increased body hair. The use of hormone therapy
to treat cancer is based on the observation that receptors for specific hormones
that are needed for cell growth are on the surface of some tumor cells. Hormone
therapies work by stopping the production of a certain hormone, blocking hormone
receptors, or substituting chemically similar agents for the active hormone, which
cannot be used by the tumor cell. The different types of hormone therapies
are categorized by their function and/or the type of hormone that is effected.
Anastozole is an aromatase inhibitor. This means it blocks the enzyme aromatase
(found in the body's muscle, skin, breast and fat), which is used to convert androgens
(hormones produced by the adrenal glands) into estrogen. In the absence of estrogen,
tumors dependent on this hormone for growth will shrink.
Note: We strongly encourage you to talk with your health care professional about
your specific medical condition and treatments. The information contained in this
website is meant to be helpful and educational, but is not a substitute for medical
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