Bladder Problems
Common Bladder Problems: Cystitis
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Hemorrhagic Cystitis
Bladder problems related to chemotherapy are mainly two types,
Cystitis and a more severe form - Hemorrhagic Cystitis.
Causes of these problems include:
- Installation of chemotherapy directly into the bladder.
- Chemotherapy given directly into the bladder is called intravesicle
(bladder) instillation. This is done by inserting a catheter
into the opening of the urethra (the tube which carries urine from the bladder to
the outside the body). When the catheter is in the bladder, the medication
will be passed through the catheter into the bladder.
- BCG is the most common chemotherapy
given by this method and is used to treat tumors on the lining of the inner bladder
wall. Other chemotherapies that may be given by this method include Mitomycin and Thiotepa.
- Two other chemotherapy medications Cyclophasphamide
and Ifosfamide are also associated
with Cystitis and Hemorrhagic Cystitis. These drugs when metabolized by the
body are converted to a substance (acrolein) that when excreted through the bladder
can cause symptoms such as irritation to the lining of the bladder.
- Radiation therapy to the pelvis can also lead to
Cystitis.
Note:
We strongly encourage you to talk with your health care professional about your
specific medical condition and treatments. The information contained in this website
about bladder problems and other medical conditions is meant to be helpful and educational,
but is not a substitute for medical advice.