LENVATINIB (len VA ti nib) treats some types of cancer. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): LENVIMA
They need to know if you have any of these conditions:
Take this medicine by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. If you are unable to swallow the capsules whole, you can mix them with water or apple juice. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.
When using capsules to make a suspension: Place the number of capsules for your dose in a small container or syringe. If your dose is more than 5 capsules, follow these directions with 3 capsules at a time. Add 3 mL of water or apple juice to the container or syringe. If you will be giving in a feeding tube, only mix with water. After 10 minutes, shake or stir until it is completely dissolved. Do not break or crush the capsules. Drink the mixture or give it through the feeding tube right away. Repeat adding another 2 mL of water or apple juice, shaking or stirring, and drinking the mixture or giving through the feeding tube right away. Repeat this at least 1 more time until you cannot see any more of the mixture left in the container or syringe.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can unless it is more than 12 hours late. If it is more than 12 hours late, skip the missed dose. Take the next dose at the normal time.
Do not take this medication with any of the following:
This medication may also interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
This medication may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
Visit your care team for regular checks on your progress. Check your blood pressure as directed. Know what your blood pressure should be and when to contact your care team.
Do not treat yourself for coughs, colds, or pain while you are using this medication without talking to your care team for advice. Some medications may increase your blood pressure.
Heart attacks and strokes have been reported with the use of this medication. Get emergency help if you develop signs or symptoms of a heart attack or stroke. Talk to your care team about the risks and benefits of this medication.
Before having surgery or dental work, talk to your care team to make sure it is ok. This medication can increase the risk of poor healing of your surgical site or wound. You will need to stop this medication for at least 1 week before surgery. After surgery, wait at least 2 weeks before restarting this medication. Make sure the surgical site or wound is healed enough before restarting this medication. Talk to your care team if questions.
Tell your dentist or dental surgeon that you are taking this medication. You should not have major dental surgery while on this medication. See your dentist to have a dental exam and fix any dental problems before starting this medication. Take good care of your teeth while on this medication. Make sure you see your dentist for regular follow-up appointments.
Some people who take this medication have severe bone, joint, or muscle pain. This medication may also increase your risk for jaw problems. Tell your care team right away if you have severe pain in your jaw. Tell your care team if you have any pain that does not go away or gets worse.
This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy. A negative pregnancy test is required before starting this medication. A reliable form of contraception is recommended while taking this medication and for 30 days after stopping it. Do not breast-feed while taking this medication and for 1 week after stopping it.
This medication may cause infertility. Talk with your care team if you are concerned about your fertility.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Store between 20 and 25 degrees C (68 and 77 degrees F). If you make a mixture with water or apple juice, store it in a covered container in the refrigerator at 2 to 8 degrees C (36 to 46 degrees F) for up to 24 hours. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Contact your health care provider immediately, day or night, and go to the emergency room, if you should experience any of the following symptoms:
The following symptoms require medical attention, but are not an emergency. Contact your health care provider within 24 hours of noticing any of the following:
Always inform your health care provider if you experience any unusual symptoms.
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