PEXIDARTINIB (PEX i DAR ti nib) treats noncancerous tumors that occur in joints. It works by blocking a protein that causes tumor cells to grow and multiply.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Turalio
They need to know if you have any of these conditions:
Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. Take with a low-fat meal. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.
Do not take this medication with grapefruit juice.
Take this medication 2 hours BEFORE or 2 hours AFTER antacids. Take this medication 2 hours BEFORE or 10 hours AFTER H2 receptor blocker medications.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
Do not take this medication with any of the following:
This medication may also interact with the following:
Take this medication 2 hours before or 2 hours after antacids to avoid decreasing its absorption.
Take this medication 2 hours before or 10 hours after H2 receptor blockers to avoid decreasing its absorption.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.
May need blood work while taking this medication.
Talk to your care team if you or your partner wish to become pregnant or think either of you might be pregnant. This medication can cause serious birth defects if taken during pregnancy and for 1 month after stopping therapy. Estrogen and progestin hormones may not work as well while you are taking this medication. A barrier contraceptive, such as a condom or diaphragm, is recommended. Talk to your care team about other forms of contraception. Do not breast-feed while taking this medication and for at least 1 week after stopping therapy.
A negative pregnancy test is required before starting this medication.
Use a condom during sex and for 1 week after stopping therapy. Tell your care team right away if you think your partner might be pregnant.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date. Protect from moisture. Keep the container tightly closed. Do not throw out the packet in the container. It keeps the medication dry.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:
The following symptoms require medical attention, but are not an emergency. Contact your health care provider within 24 hours of noticing any of the following:
Always inform your health care provider if you experience any unusual symptoms.
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